CEDONEX® Injection

• Peritonitis and other Intra-abdominal Infections
• Lower Respiratory Tract Infections including ventilator-associated pneumonia (VAP)
• Bacterial Septicemia
• Skin and Skin Structures Infections
• Bone and Joint infections
• Pelvic Inflammatory Disease & Endometritis
• Severe & complicated Urinary Tract Infections

Adults –

Usual Recommended Dosage:
CEDONEX 1.5 g Injection: 3-6 g (2-4 vials) daily in 2 divided doses (containing 2-4 g of cefoperazone with 1-2 g of sulbactam).

In Severe Infections:
CEDONEX 1.5 g Injection: up to 12 g (8 vials) daily in 2, 3, or 4 divided doses (containing cefoperazone 8 g with sulbactam 4 g).The recommended maximum daily dose of cefoperazone is 12 g in 2, 3, or 4 divided doses. The total daily dose of sulbactam should not exceed 4 g.
In cases where dose of cefoperazone needed is above 8 g, an additional cefoperazone should be administered separately. Or, as prescribed by the physician.

Pediatrics:
Usual Recommended dosage: 20-40 mg/kg/day of cefoperazone in 2 divided doses.
In severe infections: Dosage may be increased up to 160 mg/kg/day of cefoperazone in 2, 3, or 4 divided doses.
The maximum recommended daily dosage of cefoperazone is up to 200 mg/kg/day in 2, 3, or 4 divided doses. The maximum daily dose of sulbactam should not exceed 80 mg/kg/day.
Or, as prescribed by the physician.